Director: Afshin Samali, is professor of Biochemistry and director of Apoptosis Research Centre at NUI Galway. He has been working in the field of cell stress and cell death for over 20 years. His main objectives are to uncover the molecular signalling pathways activated during endoplasmic reticulum (ER) stress and unfolded protein response (UPR) and to understand the cross-talk between stress response pathways and cell death machinery and how these processes contribute to human diseases. Afshin has co-founded two other companies Triskel Therapeutics and Aquilla Biosciences and has published more than 150 publications in peer-reviewed journals, has over 11000 citations, an h-index of 46 and 7 patents. He is the editor of 3 journals and member of editorial board of another 7 journals. Afshin has also co-edited a book on “ER stress in Health and Disease”. He has managed large national/international projects, such as H2020 project TRAINERS and the FP6 project TRIDENT.
Director: Adrienne Gorman has been working in the field of cell death and survival signalling for over 20 years. Adrienne is an expert in the use of in vitro cell biology approaches to understand mechanisms of cell death and survival, including apoptosis. She has over 70 publications, h-index of 33 and over 5000 citations. Adrienne is the Vice-Dean of Research in the College of Science at NUIG and a co-ordinator of the H2020 ITN TRAINERS.
Director:Eric Chevet is Research Director at the French National Institute for Health and Medical Research (Inserm). After a Ph.D. in Molecular Cell Biology from the University of Paris XI – Orsay in 1996 and a post-doctoral fellowship at McGill University (Canada), he established his own laboratory at McGill University in 2001 before going back to Bordeaux, France in 2006. Since March 2015, he is part of the OSS lab at the CLCC Eugène Marquis, University of Rennes 1, Rennes. For the past 15 years, Eric has been investigating the role of endoplasmic reticulum stress signaling and proteostasis control in cancer development.
Co-Founder: Katarzyna Mnich is a post-doctoral researcher at the Apoptosis Research Centre at NUI Galway. She obtained her PhD in Biochemistry from the NUI Galway in 2011, in the Gorman lab. She has 9 year experience in cell survival and cell stress signaling. After PhD, she worked for 3 years on heat shock response and Endoplasmic reticulum (ER) stress in type 2 diabetes as postdoctoral researcher at the Nencki Institute of Experimental Biology (Warsaw, Poland). She subsequently developed expertise in oncology working on heat shock response and ER stress in cancer as a postdoctoral fellow at the NUIG in the Samali lab. She is an expert in molecular biology and stresses monitoring in pathological and pharmacological conditions.
Co-Founder: Susan Logue is a senior post-doctoral researcher at the Apoptosis Research Centre NUI Galway. Following completion of her PhD specialising in ER stress signaling, Susan undertook postdoctoral training investigating the cross-talk between cell death and inflammatory processes under the direction of Prof Seamus Martin. In 2012 Susan returned to the Apoptosis Research Centre in NUI Galway. Her research interests focus on understanding how the unfolded protein response intersects with inflammatory processes and the contribution this makes to diseases such as cancer.
Co-Founder: Mila Ljujic is a post-doctoral researcher at the Apoptosis Research Centre at NUI Galway. She obtained her PhD in Molecular Biology from the University of Belgrade in Serbia. During that time she was involved in both research and molecular diagnostics of alpha-1 antitrypsin deficiency and cystic fibrosis. In 2015 she received Alpha-1-Antitrypsin Laurell’s Training Award (Grifols) for the research project on the role of autophagy in alpha-1 antitrypsin deficiency. She joined Apoptosis Research Centre (ARC), NUI Galway in 2015 where she works on endoplasmic reticulum stress signalling in inflammation.
Co-Founder: Karolina Pakos-Zebrucka received her Master of Science degree in Biology, specialization in Biochemistry from University of Lodz in Poland in 2005. After graduation, she pursued her professional career in industry for eight years. In 2006, as a Fuel Formulator she completed training in R&D Analytical Chemistry Laboratory in Tel Aviv, Israel and she joined the innovative project in Medis / More Energy Ltd. The last five years she worked in Boston Scientific as a Quality Technician in the Microbiology department. During that time she gained practical experience with method development, PQ validation study and Quality Systems. She has worked to international quality standards ISO 17025, 13485, FDA 21 CFR Part 11 compliance and under GMP/GLP/GPP regulations. She joined ARC in 2013 to undertake her PhD studies under the supervision of Prof Afshin Samali.