Director: Afshin Samali, is professor of Biochemistry and director of Apoptosis Research Centre at NUI Galway. He has been working in the field of cell stress and cell death for over 20 years. His main objectives are to uncover the molecular signalling pathways activated during endoplasmic reticulum (ER) stress and unfolded protein response (UPR) and to understand the cross-talk between stress response pathways and cell death machinery and how these processes contribute to human diseases. Afshin has co-founded two other companies Triskel Therapeutics and Aquilla Biosciences and has published more than 150 publications in peer-reviewed journals, has over 11000 citations, an h-index of 46 and 7 patents. He is the editor of 3 journals and member of editorial board of another 7 journals. Afshin has also co-edited a book on “ER stress in Health and Disease”. He has managed large national/international projects, such as H2020 project TRAINERS and the FP6 project TRIDENT.
Director: Adrienne Gorman has been working in the field of cell death and survival signalling for over 20 years. Adrienne is an expert in the use of in vitro cell biology approaches to understand mechanisms of cell death and survival, including apoptosis. She has over 70 publications, h-index of 33 and over 5000 citations. Adrienne is the Vice-Dean of Research in the College of Science at NUIG and a co-ordinator of the H2020 ITN TRAINERS.
Director: Leif A. Eriksson is Professor of physical chemistry at University of Gothenburg, Sweden, since 2011. Following a chemistry BSc degree from Stockholm university 1988, he received his PhD in quantum chemistry at Uppsala university in 1992, and has since then held senior academic posts at several universities. He has published over 250 peer reviewed research papers, >20 book chapters, and has ~7000 citations and 2 patents. Eriksson’s main research focus is on the use of theoretical chemistry tools to understand structure, function and interactions of biochemical systems, with particular emphasis on drug design and protein-ligand interactions. He is involved in two Marie-Curie training networks and is also a member of the multidisciplinary center of antibacterial resistance research UGOT CARe, and currently focuses much research in the fields of cancer therapeutics and development of new antibiotics. He is the co-founder of Cell Stress Discoveries, and two other university spin-off companies.
Strategic Advisor: Eric Chevet is Research Director at the French National Institute for Health and Medical Research (Inserm). After a Ph.D. in Molecular Cell Biology from the University of Paris XI – Orsay in 1996 and a post-doctoral fellowship at McGill University (Canada), he established his own laboratory at McGill University in 2001 before going back to Bordeaux, France in 2006. Since March 2015, he is part of the OSS lab at the CLCC Eugène Marquis, University of Rennes 1, Rennes. For the past 15 years, Eric has been investigating the role of endoplasmic reticulum stress signaling and proteostasis control in cancer development.